Dravet syndrome
- Use syndrome-specific broad-spectrum therapy
- Valproate + clobazam are common foundations
- Stiripentol, cannabidiol or fenfluramine can be added
- Avoid sodium-channel blockers that can worsen SCN1A Dravet
- Rescue plan for prolonged seizures is essential
- Fever management and SUDEP counseling matter
Use at a glance
- Use syndrome-specific broad-spectrum therapy
Practical pearls
- Valproate + clobazam are common foundations
Other practical pearls
- Stiripentol, cannabidiol or fenfluramine can be added
- Rescue plan for prolonged seizures is essential
Clinical pearls
- Fever management and SUDEP counseling matter
Safety / pitfalls
- Avoid sodium-channel blockers that can worsen SCN1A Dravet
Self-check
- What treatment approach is used in Dravet syndrome?
syndrome-specific broad-spectrum therapy.
- What should generally be avoided in Dravet syndrome?
sodium-channel blockers that can worsen.
Drugs used for this (3)
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