Congenital adrenal hyperplasia (CAH)
- Replace glucocorticoid to suppress excess ACTH/androgens
- Salt-wasting disease also needs mineralocorticoid
- Infants may need sodium supplementation
- Stress-dose steroids during illness/procedures
- Avoid chronic overtreatment/Cushing effects
- Specialty monitoring includes growth, androgens + fertility
Use at a glance
- Replace glucocorticoid to suppress excess ACTH/androgens
Practical pearls
- Salt-wasting disease also needs mineralocorticoid
Treatment options
- Infants may need sodium supplementation
- Stress-dose steroids during illness/procedures
Monitoring / follow-up
- Avoid chronic overtreatment/Cushing effects
- Specialty monitoring includes growth, androgens + fertility
Self-check
- What additional replacement is needed in salt-wasting CAH?
Mineralocorticoid replacement.
- What chronic treatment problem should be avoided in CAH?
Glucocorticoid overtreatment/Cushing effects.
Drugs used for this (1)
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