Colorectal cancer
- Surgery is curative foundation for localized disease
- Adjuvant chemotherapy based on stage/risk
- Metastatic therapy uses fluoropyrimidine-based combinations
- RAS/BRAF/MSI/HER2 status can guide targeted/immunotherapy
- MSI-high tumors are especially immunotherapy-sensitive
- Resectable oligometastatic disease may still be curable
Use at a glance
- Surgery is curative foundation for localized disease
Choosing treatment
- Metastatic therapy uses fluoropyrimidine-based combinations
- RAS/BRAF/MSI/HER2 status can guide targeted/immunotherapy
- MSI-high tumors are especially immunotherapy-sensitive
Practical pearls
- Resectable oligometastatic disease may still be curable
Treatment selection
- Adjuvant chemotherapy based on stage/risk
Self-check
- What anchors localized colorectal-cancer cure?
Surgery. - Which colorectal tumors are especially immunotherapy-sensitive?
MSI-high tumors.
Drugs used for this (3)
All clinical uses · Open Colorectal cancer in the interactive console ↗