Chronic rhinosinusitis with nasal polyps (CRSwNP)
- Saline irrigation + intranasal steroid are first-line
- Short oral steroid may help severe flares
- Endoscopic sinus surgery for refractory obstruction
- Biologics for severe recurrent type-2 disease
- Dupilumab/omalizumab/mepolizumab are key options
- Treat coexisting asthma/allergy
Use at a glance
- Saline irrigation + intranasal steroid are first-line
Escalation / refractory disease
- Endoscopic sinus surgery for refractory obstruction
Practical pearls
- Dupilumab/omalizumab/mepolizumab are key options
- Treat coexisting asthma/allergy
Treatment options
- Short oral steroid may help severe flares
- Biologics for severe recurrent type-2 disease
Self-check
- What is first-line treatment for CRSwNP?
Saline irrigation + intranasal corticosteroid.
Drugs used for this (2)
All clinical uses · Open the interactive console ↗
