Beta-blocker overdose
- Stabilize airway, perfusion + rhythm
- IV fluids + vasopressor for shock
- Glucagon may improve HR/contractility
- High-dose insulin is key for severe cardiotoxicity
- Calcium can be adjunctive
- Refractory shock → lipid/ECMO in selected cases
Use at a glance
- Stabilize airway, perfusion + rhythm
Practical pearls
- Glucagon may improve HR/contractility
- Calcium can be adjunctive
Escalation / refractory disease
- Refractory shock → lipid/ECMO in selected cases
Treatment options
- IV fluids + vasopressor for shock
- High-dose insulin is key for severe cardiotoxicity
Self-check
- What is key for severe beta-blocker cardiotoxicity?
High-dose insulin. - What may treat selected refractory beta-blocker shock?
Lipid therapy/ECMO.
Drugs used for this (2)
All clinical uses · Open Beta-blocker overdose in the interactive console ↗