Aspergillosis
- Invasive disease → voriconazole is a major first-line option
- Isavuconazole is an effective alternative
- Liposomal amphotericin B for selected intolerance/resistance
- Reduce immunosuppression when feasible
- Surgery can matter for focal invasive disease
- Therapeutic drug monitoring helps selected azoles
Use at a glance
- Invasive disease → voriconazole is a major first-line option
Choosing treatment
- Reduce immunosuppression when feasible
- Surgery can matter for focal invasive disease
Practical pearls
- Isavuconazole is an effective alternative
Treatment selection
- Liposomal amphotericin B for selected intolerance/resistance
Monitoring / follow-up
- Therapeutic drug monitoring helps selected azoles
Self-check
- When can surgery matter in aspergillosis?
Focal invasive disease. - What is a major first-line option for invasive aspergillosis?
Voriconazole.
Drugs used for this (4)
All clinical uses · Open Aspergillosis in the interactive console ↗