Antidepressant discontinuation syndrome
- Reinstitute drug if symptoms are severe
- Then taper more gradually
- Short half-life serotonergic drugs cause most cases
- Fluoxetine bridging can help selected difficult tapers
- Symptoms: flu-like, dizziness, sensory, sleep changes
- Distinguish withdrawal from depressive relapse
Use at a glance
- Reinstitute drug if symptoms are severe
Treatment options
- Then taper more gradually
- Short half-life serotonergic drugs cause most cases
Practical pearls
- Symptoms: flu-like, dizziness, sensory, sleep changes
- Distinguish withdrawal from depressive relapse
Choosing treatment
- Fluoxetine bridging can help selected difficult tapers
Self-check
- What can relieve severe antidepressant withdrawal?
Reinstitute drug. - What follows reinstatement for severe antidepressant withdrawal?
A more gradual taper.
Drugs used for this (1)
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