ANCA-associated vasculitis (GPA/MPA)
- Induce remission with glucocorticoid + rituximab/cyclophosphamide
- Rituximab is preferred in many relapsing/PR3 cases
- Avacopan can reduce glucocorticoid exposure
- Plasma exchange only for selected severe situations
- Maintain remission with rituximab or other immunosuppressant
- Prophylax infection/bone complications during intensive therapy
Use at a glance
- Induce remission with glucocorticoid + rituximab/cyclophosphamide
Practical pearls
- Rituximab is preferred in many relapsing/PR3 cases
Treatment options
- Avacopan can reduce glucocorticoid exposure
- Prophylax infection/bone complications during intensive therapy
Choosing treatment
- Plasma exchange only for selected severe situations
- Maintain remission with rituximab or other immunosuppressant
Self-check
- Which drug is preferred in many relapsing/PR3 ANCA-vasculitis cases?
Rituximab. - Which drug can reduce glucocorticoid exposure in ANCA vasculitis?
Avacopan.
Drugs used for this (2)
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