Anaphylaxis
- IM epinephrine is first and lifesaving
- Give in lateral thigh; repeat if needed
- Airway, oxygen, IV fluid + monitoring next
- Antihistamines treat hives—not shock
- Steroids do not replace epinephrine
- Biphasic risk determines observation
- Discharge with epinephrine + trigger plan
Use at a glance
- IM epinephrine is first and lifesaving
Practical pearls
- Antihistamines treat hives—not shock
Choosing treatment
- Give in lateral thigh; repeat if needed
- Discharge with epinephrine + trigger plan
Monitoring / follow-up
- Airway, oxygen, IV fluid + monitoring next
- Steroids do not replace epinephrine
- Biphasic risk determines observation
Self-check
- What is first-line for anaphylaxis?
IM epinephrine. - Do antihistamines treat anaphylactic shock?
No—hives, not shock.
Drugs used for this (1)
All clinical uses · Open Anaphylaxis in the interactive console ↗