Amyotrophic lateral sclerosis (ALS)
- Multidisciplinary supportive care improves outcomes
- Riluzole modestly prolongs survival
- Edaravone is another disease-modifying option
- Tofersen only for SOD1-mutated ALS
- Noninvasive ventilation has major survival benefit
- Treat sialorrhea, spasticity + PBA
- Discuss nutrition/communication early
Use at a glance
- Multidisciplinary supportive care improves outcomes
Practical pearls
- Riluzole modestly prolongs survival
Other practical pearls
- Edaravone is another disease-modifying option
- Tofersen only for SOD1-mutated ALS
Clinical pearls
- Noninvasive ventilation has major survival benefit
- Treat sialorrhea, spasticity + PBA
- Discuss nutrition/communication early
Self-check
- What should be treated in Amyotrophic lateral sclerosis (ALS)?
sialorrhea, spasticity + PBA.
- What improves outcomes in Amyotrophic lateral sclerosis (ALS)?
Multidisciplinary supportive care.
Drugs used for this (2)
All clinical uses · Open the interactive console ↗
