Akathisia (antipsychotic-induced)
- Reduce dose or switch antipsychotic if feasible
- Propranolol has the best-established drug role
- Short-term benzodiazepine can help selected patients
- Mirtazapine/5-HT2A blockade is another option
- Antimuscarinics help less unless parkinsonism coexists
- Distinguish akathisia from anxiety/agitation
Use at a glance
- Reduce dose or switch antipsychotic if feasible
Treatment options
- Propranolol has the best-established drug role
- Mirtazapine/5-HT2A blockade is another option
Practical pearls
- Antimuscarinics help less unless parkinsonism coexists
- Distinguish akathisia from anxiety/agitation
Choosing treatment
- Short-term benzodiazepine can help selected patients
Self-check
- What medication adjustment should be considered first in Akathisia (antipsychotic-induced)?
Reduce the dose or switch antipsychotic.
Drugs used for this (1)
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