Agitation associated with Alzheimer disease

First identify pain, delirium + unmet needs
Non-drug behavioral/environmental measures first
Severe persistent agitation → drug may be needed
Brexpiprazole is FDA-approved for this use
Antipsychotics carry mortality/stroke warnings
Use lowest effective dose; reassess frequently
Do not medicate simple wandering alone

Use at a glance

First identify pain, delirium + unmet needs

Treatment options

Non-drug behavioral/environmental measures first

Practical pearls

Brexpiprazole is FDA-approved for this use

Other treatment options

Severe persistent agitation → drug may be needed

Monitoring / follow-up

Antipsychotics carry mortality/stroke warnings
Use lowest effective dose; reassess frequently
Do not medicate simple wandering alone

Self-check

What treatment approach is used in Agitation associated with Alzheimer disease?
lowest effective dose; reassess frequently.
What should be done first in Agitation associated with Alzheimer disease?
identify pain, delirium + unmet needs.

Drugs used for this (1)

Brexpiprazole ballicule — decagon mechanism diagram — Brexpiprazole

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