Acromegaly
- Transsphenoidal surgery if resectable adenoma
- Persistent disease → medical therapy
- somatostatin analog or paltusotine
- Pegvisomant if IGF-1 remains high
- Cabergoline for selected mild disease
- Radiation is later-line
- Follow IGF-1 + tumor/comorbidity burden
Use at a glance
- Transsphenoidal surgery if resectable adenoma
Escalation / refractory disease
Treatment options
- Persistent disease → medical therapy
- somatostatin analog or paltusotine
Choosing treatment
- Pegvisomant if IGF-1 remains high
- Cabergoline for selected mild disease
Monitoring / follow-up
- Follow IGF-1 + tumor/comorbidity burden
Self-check
- What should be followed during treatment of Acromegaly?
IGF-1 + tumor/comorbidity burden.
- What is recommended for Persistent disease in Acromegaly?
medical therapy.
Drugs used for this (3)
All clinical uses · Open the interactive console ↗
