Acromegaly
- Transsphenoidal surgery if resectable adenoma
- Persistent disease → medical therapy
- somatostatin analog or paltusotine
- Pegvisomant if IGF-1 remains high
- Cabergoline for selected mild disease
- Radiation is later-line
- Follow IGF-1 + tumor/comorbidity burden
Use at a glance
- Transsphenoidal surgery if resectable adenoma
Escalation / refractory disease
- Radiation is later-line
Treatment options
- Persistent disease → medical therapy
- somatostatin analog or paltusotine
Choosing treatment
- Pegvisomant if IGF-1 remains high
- Cabergoline for selected mild disease
Monitoring / follow-up
- Follow IGF-1 + tumor/comorbidity burden
Self-check
- What is followed during acromegaly treatment?
IGF-1 + tumor/comorbidity burden. - What is used if IGF-1 remains high in acromegaly?
Pegvisomant.
Drugs used for this (4)
All clinical uses · Open Acromegaly in the interactive console ↗