Precursor to metabolite: Procainamide to NAPA

Procainamide is converted to NAPA by NAT2.

Procainamide mascot — mnemonic cartoon — Visual mnemonic: Procainamide mascot

The pair

Procainamide — Class IA antiarrhythmic; drug-induced lupus with chronic use.
NAPA — N-acetylprocainamide, an active procainamide metabolite with class III effects; renal accumulation increases QT-prolongation risk.

Procainamide · NAPA · Open Procainamide in the interactive console ↗