Precursor to metabolite: Milsaperidone to Iloperidone

Milsaperidone is converted to Iloperidone by oxidation (reverse of the ketone reduction that forms it).

Milsaperidone mascot — mnemonic cartoon — Visual mnemonic: Milsaperidone mascot

Iloperidone mascot — mnemonic cartoon — Visual mnemonic: Iloperidone mascot

The pair

Milsaperidone — Active iloperidone metabolite for schizophrenia and bipolar mania; QT and orthostasis.
Iloperidone — Atypical requiring slow titration for orthostasis; QT prolongation.

Milsaperidone · Iloperidone · Open Milsaperidone in the interactive console ↗