Precursor to metabolite: Hydroxyzine HCl to Cetirizine

Hydroxyzine HCl is converted to Cetirizine by alcohol/aldehyde dehydrogenase.

Hydroxyzine HCl mascot — mnemonic cartoon — Visual mnemonic: Hydroxyzine HCl mascot

Cetirizine mascot — mnemonic cartoon — Visual mnemonic: Cetirizine mascot

The pair

Hydroxyzine HCl — Sedating H1 blocker used for pruritus and short-term anxiety.
Cetirizine — Fast, effective second-generation H1 antihistamine; more sedating than its peers.

Hydroxyzine HCl · Cetirizine · Open Hydroxyzine HCl in the interactive console ↗