Precursor to metabolite: Venlafaxine XR to Desvenlafaxine
Venlafaxine XR is converted to Desvenlafaxine by CYP2D6.
The pair
- Venlafaxine XR — Extended-release SNRI for depression and anxiety; withdrawal and hypertension limit it.
- Desvenlafaxine — Active metabolite of venlafaxine; more balanced SNRI with simpler kinetics.
Anything that inhibits or induces CYP2D6 shifts the balance between Venlafaxine XR and Desvenlafaxine.
Venlafaxine XR · Desvenlafaxine · Open Venlafaxine XR in the interactive console ↗