Y1 agonist
Neuropeptide Y1 receptor agonist
- Vasoconstriction
- If BBB-crossing:
- Anxiolysis
- ↑ appetite
- Opposes the presynaptic inhibitory Y2 arm
Drugs with this mechanism (1)
- Neuropeptide Y — Abundant CNS peptide; powerful appetite stimulant.
Self-check
- Which listed endogenous peptide activates Y1?
Neuropeptide Y. - What has blocked development of approved NPY-targeted drugs?
Peptide delivery.
All mechanisms · Open Y1 agonist in the interactive console ↗