Unknown target
Unknown clinical target
- Clinical effect established; molecular target unidentified
- Placeholder for mechanisms not yet mapped to a receptor or enzyme
- Pyrazinamide is the library’s one genuine unknown: fatty-acid synthase I, ribosomal trans-translation and membrane depolarization by pyrazinoic acid all have support, and none is settled
Drugs with this mechanism (1)
- Pyrazinamide — First-line tuberculosis drug; mechanism contested. Fatty-acid synthase I, ribosomal trans-translation, and membrane depolarization by pyrazinoic acid all have support; none settled. Limited by hepatotoxicity and hyperuricemia.
Self-check
- Which library drug has a genuinely unsettled molecular mechanism here?
Pyrazinamide. - Name one supported but unsettled candidate mechanism for pyrazinamide.
Fatty-acid synthase I as a target.
All mechanisms · Open Unknown target in the interactive console ↗