TTR stabilizer

Transthyretin (TTR) tetramer stabilizer

Stabilizes transthyretin tetramers → prevents dissociation/misfolding into amyloid

Drugs with this mechanism (2)

Acoramidis — Oral transthyretin stabilizer that holds the TTR tetramer together in ATTR cardiomyopathy.
Tafamidis — Stabilizes the transthyretin tetramer in ATTR cardiomyopathy.

All mechanisms · Open the interactive console ↗