Spinal reflex inhibitor
Spinal polysynaptic reflex inhibitor
- Muscle relaxation with no direct muscle action
- Sedation accompanies the same central depression
- Mechanism not fully defined
Drugs with this mechanism (1)
- Chlorzoxazone — Relatively nonsedating central muscle relaxant; rare idiosyncratic hepatotoxicity.
Self-check
- Which listed central muscle relaxant has this incompletely defined mechanism?
Chlorzoxazone. - Which potentially fatal toxicity can occur with chlorzoxazone?
Idiosyncratic hepatotoxicity.
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