sGC stimulator

Soluble guanylate cyclase stimulator

Contraindicated with nitrates and PDE5 inhibitors

Drugs with this mechanism (3)

Nitric oxide — Endogenous gasotransmitter; inhaled for pulmonary hypertension in newborns.
Riociguat — Soluble guanylate cyclase stimulator for pulmonary hypertension.
Vericiguat — Soluble guanylate cyclase stimulator for worsening heart failure.

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