Thallium/cesium sequestrant
- Traps thallium and cesium in the gut, interrupting enterohepatic recycling
- Both metals are carried out in stool → shortened biological half-life
- The specific antidote for thallium and radioactive cesium (Cs-137) exposure
Drugs with this mechanism (1)
- Prussian blue — Nonabsorbed intestinal binder for radioactive cesium and thallium poisoning; accelerates fecal elimination and can cause constipation.
Self-check
- Which recycling pathway is interrupted by gut binding of thallium and cesium?
Enterohepatic recycling. - Through which route are the bound metals eliminated?
Stool.
All mechanisms · Open Thallium sequestrant in the interactive console ↗