Phosphate binder
- ↓ dietary phosphate absorption from the gut lumen
- Controls hyperphosphatemia in chronic kidney disease
- Nonselective binding can also trap other drugs — separate dosing
Drugs with this mechanism (2)
- Lanthanum carbonate — Chewable, noncalcium phosphate binder for dialysis; lower pill burden than sevelamer.
- Sevelamer — Nonabsorbed phosphate binder for dialysis; avoids calcium load but binds other drugs.
Self-check
- In which chronic disease is this phosphate-binding role described?
Chronic kidney disease. - Why separate other drugs from phosphate binders?
Nonselective binding can trap them.
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