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Mechanisms
› Phosphate binder
Phosphate binder
Binds dietary phosphate in the gut lumen
Binding is non-selective — other drugs are bound too
Drugs with this mechanism (2)
Lanthanum carbonate
— Chewable, noncalcium phosphate binder for dialysis; lower pill burden than sevelamer.
Sevelamer
— Nonabsorbed phosphate binder for dialysis; avoids calcium load but binds other drugs.
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