Iron chelator
- Chelates iron in overload states and acute poisoning
Drugs with this mechanism (3)
- Deferasirox — Oral iron chelator for chronic transfusional iron overload; renal, hepatic, and GI toxicity.
- Deferiprone — Oral iron chelator for transfusional iron overload; potentially fatal agranulocytosis requires neutrophil monitoring.
- Deferoxamine — Injectable iron chelator for acute iron poisoning and chronic overload; prolonged therapy can damage hearing and vision.
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