RET/VEGFR inhibitor
RET and VEGFR kinase inhibitor
- Hypertension, bleeding, impaired wound healing
Drugs with this mechanism (3)
- Pralsetinib — Selective RET inhibitor for RET-driven cancers; monitor for hypertension, hepatotoxicity, and pneumonitis.
- Regorafenib — Oral multikinase inhibitor for refractory colorectal and GIST tumors.
- Vandetanib — RET/VEGFR inhibitor for medullary thyroid cancer; QT prolongation.
All mechanisms · Open the interactive console ↗