PAF antagonist
Platelet-activating factor receptor antagonist
- ↓ inflammatory and vascular responses
- ↓ PAF-induced platelet aggregation
Drugs with this mechanism (1)
- Ginkgolide B — Ginkgo terpene lactone and a potent platelet-activating factor antagonist — the basis of the bleeding concern.
Self-check
- Which platelet response does PAF-receptor blockade reduce?
PAF-induced aggregation. - Which non-platelet responses does PAF blockade reduce?
Inflammatory and vascular responses.
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