NMDA polyamine-site antagonist

NMDA receptor polyamine-site antagonist

Blocks the polyamine modulatory site on the NMDA receptor

Drugs with this mechanism (2)

Acamprosate — Glutamate-modulating agent for maintaining alcohol abstinence; renally cleared.
Agmatine — Endogenous polyamine; NMDA and imidazoline modulator sold as a supplement.

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