NMDA glycine-site antagonist

NMDA receptor glycine-site antagonist

Felbamate; kynurenic acid is the endogenous ligand

Drugs with this mechanism (2)

Felbamate — Broad anticonvulsant restricted for aplastic anemia and hepatotoxicity.
Kynurenic acid — Endogenous NMDA glycine-site antagonist and tryptophan metabolite.

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