NADPH: biosynthesis
- Fuels fatty-acid, cholesterol and nucleotide synthesis
- Supplied largely by the pentose phosphate pathway
Drugs with this mechanism (1)
- NADP — Phosphorylated NAD coenzyme; its reduced form, NADPH, supports biosynthesis and antioxidant defenses.
Self-check
- Which pathway supplies much of the NADPH used for synthesis?
The pentose phosphate pathway. - Name a biosynthetic process fueled by NADPH.
Fatty-acid, cholesterol or nucleotide synthesis.
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