Neuronal nAChR allosteric potentiator (APL)
Neuronal nicotinic receptor allosteric potentiating ligand
Neuronal nAChR allosteric potentiator (APL) — mechanism card
- Allosteric potentiating ligand: sensitizes nAChRs to acetylcholine without activating them
- No nicotine-like reinforcement
- A minor contributor next to acetylcholinesterase inhibition
- Allosteric potentiating ligand: sensitizes nAChRs to acetylcholine without activating them
- No nicotine-like reinforcement
- A minor contributor next to acetylcholinesterase inhibition
Drugs with this mechanism (1)
- Galantamine — Cholinesterase inhibitor that also modulates nicotinic receptors.
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