Cardiac myosin inhibitor
- Reduces excessive cardiac contractility
- Over-inhibition produces systolic dysfunction
Drugs with this mechanism (2)
- Aficamten — Shorter-acting cardiac myosin inhibitor for obstructive HCM; echo monitoring guards against systolic failure.
- Mavacamten — Cardiac myosin inhibitor for obstructive hypertrophic cardiomyopathy.
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