Membrane fluidity modulator
- Incorporation into membrane phospholipids alters bilayer fluidity
- Alters embedded receptors and ion channels — an antiarrhythmic rationale
Drugs with this mechanism (2)
- Icosapent ethyl — Purified EPA omega-3 that lowers triglycerides and cardiovascular events.
- Omega-3 fatty acids — Mixed EPA/DHA lowers triglycerides but can raise LDL; OTC products are not equivalent.
Self-check
- How are membrane-fluidity effects produced?
Incorporation into membrane phospholipids. - What embedded proteins are affected by altered membrane fluidity?
Receptors and ion channels.
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