Membrane depolarizer
Calcium-dependent bacterial membrane depolarizer
- Calcium-dependent depolarization of the bacterial membrane
- Sequestered and inactivated by pulmonary surfactant
- Skeletal muscle myopathy
Drugs with this mechanism (1)
- Daptomycin — Lipopeptide that depolarizes gram-positive membranes; inactivated by surfactant, so never for pneumonia.
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