Methionine synthase methyl donor
- The active folate
- Bypasses the MTHFR enzyme step — usable regardless of genotype
- Supports homocysteine clearance and one-carbon metabolism
- Methionine synthase methyl donor
Drugs with this mechanism (1)
- L-Methylfolate — Active folate methyl donor; used to augment antidepressants.
Self-check
- Which enzyme step does L-methylfolate bypass?
MTHFR. - Which clearance process does L-methylfolate support?
Homocysteine clearance.
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