GPR35 agonist
- A receptor for kynurenic acid
- Modulates immune and inflammatory signaling
- ↓ inflammation
- A link between tryptophan metabolism and immunity
Drugs with this mechanism (1)
- Kynurenic acid — Endogenous NMDA glycine-site antagonist and tryptophan metabolite.
Self-check
- Which endogenous ligand is recognized by GPR35?
Kynurenic acid. - Which metabolic pathway does GPR35 link to immunity?
Tryptophan metabolism.
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