Glutamate-gated Cl channel agonist

Invertebrate glutamate-gated chloride channel agonist

Opens invertebrate chloride channels — parasite paralysis
Mammals are spared: these channels are absent and the blood-brain barrier excludes it

Drugs with this mechanism (1)

Ivermectin — Antiparasitic opening invertebrate glutamate-gated chloride channels.

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