GHRH agonist
GHRH receptor agonist
- Stimulates physiologic, pulsatile growth-hormone release
- Tests and treats the axis upstream of growth hormone itself
Drugs with this mechanism (1)
- Sermorelin — GHRH analog stimulating the pituitary’s own GH release; no FDA-approved product remains.
Self-check
- What release pattern does GHRH stimulation produce?
Physiologic, pulsatile GH release. - Does GHRH act upstream or downstream of growth hormone itself?
Upstream.
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