GH receptor agonist
Growth hormone receptor agonist
- ↑ IGF-1 (insulin-like growth factor 1)
- Restores growth and anabolic signaling in deficiency
- Fluid retention, insulin resistance
- Contraindicated with active malignancy
Drugs with this mechanism (1)
- Somatropin — Recombinant growth-hormone replacement for deficiency and selected growth disorders.
Self-check
- Which growth factor rises with GH receptor activation?
IGF-1. - What malignancy status contraindicates GH receptor agonism?
Active malignancy.
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