G-CSF agonist

G-CSF receptor agonist

Stimulates neutrophil production after chemotherapy
Bone pain; rare splenic rupture

Drugs with this mechanism (2)

Filgrastim — Recombinant G-CSF that shortens chemotherapy-induced neutropenia.
Pegfilgrastim — Long-acting G-CSF agonist preventing febrile neutropenia after myelosuppressive chemotherapy.

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