GAT-1 inhibitor

GABA transporter 1 reuptake inhibitor

Inhibits GABA transporter 1 (GAT1)
➔ antiepileptic drug
➔ off-label for social anxiety disorder
➔ may alter color perception ◇ brighter blues/greens ◇ via GABA-C receptors in retina

Drugs with this mechanism (1)

Tiagabine — GAT-1 inhibitor that raises synaptic GABA; adjunctive anticonvulsant with paradoxical seizure risk.

All mechanisms · Open the interactive console ↗