Benzodiazepine-site antagonist
GABA-A benzodiazepine-site antagonist
- Reverses benzodiazepine sedation
- Can precipitate seizures/withdrawal in the benzodiazepine-dependent
Drugs with this mechanism (1)
- Flumazenil — Benzodiazepine-site antagonist; reverses benzodiazepine sedation, seizure risk.
Self-check
- What effect can benzodiazepine-site antagonism reverse?
Benzodiazepine sedation. - What can reversal precipitate in a benzodiazepine-dependent patient?
Seizures or withdrawal.
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