Endonuclease inhibitor
Influenza cap-dependent endonuclease inhibitor
- Blocks influenza cap-dependent endonuclease — the “cap-snatching” enzyme
- Single-dose baloxavir
- Viral mRNA synthesis fails
- A different target from neuraminidase inhibitors
Drugs with this mechanism (1)
- Baloxavir marboxil — Single-dose influenza endonuclease inhibitor.
Self-check
- What viral synthesis fails when influenza cap-snatching is blocked?
Viral mRNA synthesis. - Which influenza antiviral uses a single-dose regimen here?
Baloxavir.
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