Pancreatic enzyme replacement
- Replaces pancreatic lipase, protease and amylase
- Restores fat/protein digestion in pancreatic insufficiency
- Works only when taken with food; dose scales with fat intake
Drugs with this mechanism (2)
- Pancrelipase — Porcine pancreatic enzyme replacement for exocrine insufficiency.
- Pancrelipase tablet — Non-enteric-coated pancrelipase tablet; must be paired with a PPI; adults with chronic pancreatitis or pancreatectomy.
Self-check
- When must pancreatic digestive enzymes be taken to work?
With food. - What determines pancreatic-enzyme dose scaling here?
Fat intake.
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