BChE inhibitor
Butyrylcholinesterase (BChE) inhibitor
- ↓ acetylcholine degradation by plasma pseudocholinesterase (BChE)
- Additive with acetylcholinesterase inhibition
- BChE gains importance in advanced dementia as glial BChE rises
Drugs with this mechanism (1)
- Rivastigmine — Cholinesterase inhibitor available as a patch; also for Parkinson dementia.
Self-check
- How does BChE inhibition affect acetylcholine degradation?
Decreases it. - Why does BChE inhibition gain relevance in advanced dementia?
Glial BChE rises.
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