BRAF inhibitor

BRAF kinase inhibitor

Targets BRAF V600E melanoma

Drugs with this mechanism (3)

Dabrafenib — BRAF V600 inhibitor; paradoxically activates the pathway in BRAF-wild-type cells.
Sorafenib — Multikinase inhibitor for selected liver, kidney, and thyroid cancers; hand-foot skin reaction, diarrhea, and hypertension are prominent.
Vemurafenib — BRAF inhibitor for BRAF-V600E melanoma.

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