Arthropod Nav opener
Arthropod sodium channel prolonged opener
- Repetitive firing → paralysis of the parasite
- Holds arthropod sodium channels open
- Kills lice, mites and other arthropods on contact
- Mammalian sodium channels are far less sensitive — the basis of safety
Drugs with this mechanism (1)
- Permethrin — Pyrethroid scabicide and pediculicide; prolongs arthropod sodium channel opening.
Self-check
- What does repetitive firing cause in the arthropod?
Paralysis. - Why are mammals less susceptible to arthropod sodium-channel openers?
Mammalian sodium channels are far less sensitive.
All mechanisms · Open Arthropod NaV opener in the interactive console ↗