5-HT1B/1D antagonist

5-HT1B/1D serotonin receptor antagonist

Opposite effect of triptans, but 5-HT1B/D blockers do not tend to cause headache

Drugs that bind this target

vortioxetine (TRINTELLIX)

No ballicule in the library carries this peg — no selective agent is clinically available, so the binding is shown here rather than on a card.

Self-check

Which migraine drug class has the opposite receptor effect to 5-HT1B/1D blockers?
Triptans.
Do 5-HT1B/1D blockers tend to cause headache?
No.

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