OAT1 substrate
- Substrate of OAT1
- OAT1 renal organic-anion transporter
- Transporter changes can alter exposure/distribution
- Inhibitors may raise or lower AUC by transporter role
- Kidney/liver/GI location determines direction
Interaction at a glance
- Substrate of OAT1
- OAT1 renal organic-anion transporter
Mechanism
- Substrate of OAT1
- OAT1 renal organic-anion transporter
Magnitude / time course
- Inhibitors may raise or lower AUC by transporter role
- Kidney/liver/GI location determines direction
Exposure modifiers
- Transporter changes can alter exposure/distribution
Self-check
- What does “OAT1 substrate” mean?
Substrate of OAT1.
Drugs in this interaction (3)
All interaction examples · Open the interactive console ↗
