MATE2-K substrate
- Substrate of MATE2-K
- Transporter changes can alter exposure/distribution
- Inhibitors may raise or lower AUC by transporter role
- Kidney/liver/GI location determines direction
Interaction at a glance
Mechanism
Magnitude / time course
- Inhibitors may raise or lower AUC by transporter role
- Kidney/liver/GI location determines direction
Exposure modifiers
- Transporter changes can alter exposure/distribution
Self-check
- What does “MATE2-K substrate” mean?
Substrate of MATE2-K.
Drugs in this interaction (2)
All interaction examples · Open the interactive console ↗
